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Items: 3

1.

Gene expression profiles of Lgr5-GFP high and Lgr5-GFP low cells in small intestines of Itgb7+/+ Lgr5-GFP mice and Itgb7-/- Lgr5-GFP mice

(Submitter supplied) Intestinal stem cell (ISC) differentiation is regulated precisely by a niche in the crypt, where lymphocytes may interact with stem and transient amplifying (TA) cells. However, whether and how lymphocyte-stem/TA cell contact affects ISC differentiation is largely unknown. Here, we uncover a novel role of T cell-stem/TA cell contact in ISC fate decisions. We show that intestinal lymphocyte depletion results in skewed ISC differentiation in mice, which can be rescued by T cell transfer. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL24247
20 Samples
Download data: TXT
Series
Accession:
GSE133691
ID:
200133691
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

Lgr5low-Itgb7 KO-3

Organism:
Mus musculus
Source name:
small intestine
Platform:
GPL24247
Series:
GSE133691
Download data
Sample
Accession:
GSM3916316
ID:
303916316
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db=gds|term=GSM3916316[Accession]|query=1|qty=2|blobid=MCID_678fba5df5211606905ad7ee|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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