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Items: 3

1.

TWIST1 is required for HSC maintenance under steady state and stress condition by inhibiting mitochondrial metabolism gene program

(Submitter supplied) RNA-seq and ATAC-seq were performed to determine possible downstream molecular mechamisms and the changes in chromatin accessibility in long-term hematopoietic stem cell when TWIST1 was absent following irradiation stress. We found that mitochondrial metabolism pathway was strongly turned on in the Twist1-deficient LT-HSCs upon irradiation stress.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL21103
6 Samples
Download data: BW, TXT
Series
Accession:
GSE133682
ID:
200133682

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2.

Illumina HiSeq 4000 (Mus musculus)

Organism:
Mus musculus
6634 Series
142623 Samples
Download data
Platform
Accession:
GPL21103
ID:
100021103

3.

ATAC-seq_IR_KO

Organism:
Mus musculus
Source name:
Lineage–Sca1+cKit+CD34–Flk2– long-term hematopoietic stem cells
Platform:
GPL21103
Series:
GSE133682
Download data: BW
Sample
Accession:
GSM3914420
ID:
303914420

SRA Run Selector

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db=gds|term=GSM3914420[Accession]|query=1|qty=2|blobid=MCID_675bc3488a8772128d17b0c6|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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