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Items: 4

1.

Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL17021 GPL24676 GPL24247
123 Samples
Download data: BED
Series
Accession:
GSE131583
ID:
200131583
2.

Combined Cohesin-Runx1 Deficiency Synergistically Perturbs Chromatin Looping and Causes Myelodysplastic Syndromes [ChIP-seq]

(Submitter supplied) STAG2 encodes a cohesin component and is frequently mutated in myeloid neoplasms, showing highly significant co-mutation patterns with other drivers, including RUNX1. However, the molecular basis of cohesin-mutated leukemogenesis remains poorly understood. Here we show a critical role of an interplay between Stag2 and Runx1 in the regulation of enhancer-promoter looping and transcription in hematopoiesis. more...
Organism:
Mus musculus; Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL24676 GPL24247 GPL17021
52 Samples
Download data: BED
Series
Accession:
GSE131577
ID:
200131577
3.

Illumina HiSeq 2500 (Mus musculus)

Platform
Accession:
GPL17021
ID:
100017021
4.

ChIP_HSPC_H3K4me3_WT_rep2

Organism:
Mus musculus
Source name:
bone marrow cells
Platform:
GPL17021
Series:
GSE131577 GSE131583
Download data: BED
Sample
Accession:
GSM3790124
ID:
303790124
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Supplemental Content

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