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Items: 4

1.

Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Other; Genome variation profiling by genome tiling array; Genome variation profiling by high throughput sequencing
4 related Platforms
111 Samples
Download data: PAIR
Series
Accession:
GSE130374
ID:
200130374
2.

Replication timing alterations in leukemia reflect stable clinically-relevant changes in genome architecture [Repli-Seq]

(Submitter supplied) Human B-lineage precursor acute lymphoid leukemias (BCP-ALLs) comprise a group of genetically and clinically distinct disease entities with features of differentiation arrest at known stages of normal B-lineage differentiation. We previously showed BCP-ALL cells display unique and clonally heritable DNA-replication timing (RT) programs; i.e., programs describing the variable order of replication and sub-nuclear 3D architecture of megabase-scale chromosomal units of DNA in different cell types. more...
Organism:
Homo sapiens
Type:
Other; Third-party reanalysis; Genome variation profiling by high throughput sequencing
Platform:
GPL16791
48 Samples
Download data: TXT
Series
Accession:
GSE130373
ID:
200130373
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

X697R5-Late S Fraction

Organism:
Homo sapiens
Source name:
cell line 697
Platform:
GPL16791
Series:
GSE130373 GSE130374
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Sample
Accession:
GSM3737053
ID:
303737053
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