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Items: 4

1.

IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards pathogenic CD11c+ macrophage phenotype

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21103 GPL24247
24 Samples
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Series
Accession:
GSE129258
ID:
200129258
2.

IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards pathogenic CD11c+ macrophage phenotype [small_bulk_rnaseq]

(Submitter supplied) Mononuclear phagocytes (MNPs) play a key role in maintaining intestinal homeostasis but also in triggering immunopathology in response to acute microbial stimulation, which induces the recruitment of masses of Ly6Chi monocytes to the gut. The regulators that control monocyte tissue adaptation in the gut remain poorly understood. Interferon Regulatory Factor 5 (IRF5) is a transcription factor previously shown to play a key role in maintaining the inflammatory phenotype of macrophages Here we investigate the impact of IRF5 on the MNP system and physiology of the gut at homeostasis and during inflammation. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
18 Samples
Download data: TXT
Series
Accession:
GSE129257
ID:
200129257
3.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
4.

cLP_p1mono_wt_hh_S2

Organism:
Mus musculus
Source name:
colonic lamina propria
Platform:
GPL21103
Series:
GSE129257 GSE129258
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Sample
Accession:
GSM3703654
ID:
303703654
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Supplemental Content

db=gds|term=GSM3703654[Accession]|query=1|qty=2|blobid=MCID_662638174c13c13a06803182|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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