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Items: 4

1.

Variant PRC2.1 and PRC2.2 co-operate to direct H3K27 methylations in ESCs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster; Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL25537 GPL19057 GPL19415
79 Samples
Download data: BW
Series
Accession:
GSE127121
ID:
200127121
2.

Variant PRC2.1 and PRC2.2 co-operate to direct H3K27 methylations in ESCs [RNA-seq]

(Submitter supplied) Polycomb repressive complex 2 (PRC2) is composed of EED, SUZ12, and EZH1/2, and mediates mono-, di- and tri-methylation of Histone H3 at Lysine 27. While, two subcomplexes defined by their specific accessory proteins, termed PRC2.1 (Polycomb-like proteins 1-3, EPOP and PALI1/2) and PRC2.2 (AEBP2 and JARID2) exist, little is known about their differential functions. Here, we show that PRC2.1 and PRC2.2 share the majority of their target genes in mouse embryonic stem cells (ESCs). more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
20 Samples
Download data: BW
Series
Accession:
GSE127119
ID:
200127119
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

WT_EB_D8_rep1

Organism:
Mus musculus
Source name:
Embryoid Body
Platform:
GPL19057
Series:
GSE127119 GSE127121
Download data: BW
Sample
Accession:
GSM3625728
ID:
303625728
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Supplemental Content

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