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Items: 4

1.

Variant PRC2.1 and PRC2.2 co-operate to direct H3K27 methylations in ESCs

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Drosophila melanogaster; Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL25537 GPL19057 GPL19415
79 Samples
Download data: BW
Series
Accession:
GSE127121
ID:
200127121
2.

Variant PRC2.1 and PRC2.2 co-operate to direct H3K27 methylations in ESCs [ChIP-seq]

(Submitter supplied) Polycomb repressive complex 2 (PRC2) is composed of EED, SUZ12, and EZH1/2, and mediates mono-, di- and tri-methylation of Histone H3 at Lysine 27. While, two subcomplexes defined by their specific accessory proteins, termed PRC2.1 (Polycomb-like proteins 1-3, EPOP and PALI1/2) and PRC2.2 (AEBP2 and JARID2) exist, little is known about their differential functions. Here, we show that PRC2.1 and PRC2.2 share the majority of their target genes in mouse embryonic stem cells (ESCs). more...
Organism:
Homo sapiens; Mus musculus; Drosophila melanogaster
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19415 GPL25537
22 Samples
Download data: BW
Series
Accession:
GSE127117
ID:
200127117
3.

Illumina NextSeq 500 (Homo sapiens; Mus musculus)

Organism:
Homo sapiens; Mus musculus
93 Series
1635 Samples
Download data
Platform
Accession:
GPL19415
ID:
100019415
4.

WT_SUZ12

Organism:
Mus musculus; Homo sapiens
Source name:
Embryonic stem cell and NT2 cell line
Platform:
GPL19415
Series:
GSE127117 GSE127121
Download data: BW
Sample
Accession:
GSM3625701
ID:
303625701
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Supplemental Content

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