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Items: 4

1.

p53 activates the long noncoding RNA Pvt1b to inhibit Myc and suppress tumorigenesis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL24247 GPL21103
31 Samples
Download data: BEDGRAPH
Series
Accession:
GSE143204
ID:
200143204
2.

p53 activates the long noncoding RNA Pvt1b to inhibit Myc and suppress tumorigenesis

(Submitter supplied) P53 activation in response to cellular stress has long been known to result in downregulation of c-myc, a gene that is frequently overexpressed in cancer due to its role in promoting cellular proliferation. However, the mechanism underlying this p53 dependent myc repression is poorly understood. Here we report p53 regulation of the lncRNA PVT1, a neighboring myc gene which is upregulated following p53 activation via p53 binding to a canonical p53 response element (p53RE) in the first intron of PVT1. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21103
12 Samples
Download data: TXT
Series
Accession:
GSE126940
ID:
200126940
3.

Illumina HiSeq 4000 (Mus musculus)

Platform
Accession:
GPL21103
ID:
100021103
4.

ND_3_rep1

Organism:
Mus musculus
Source name:
mouse embryonic fibroblasts
Platform:
GPL21103
Series:
GSE126940 GSE143204
Download data
Sample
Accession:
GSM3618446
ID:
303618446
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Supplemental Content

db=gds|term=GSM3618446[Accession]|query=1|qty=2|blobid=MCID_67312cc67bb3c5468945be6a|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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