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Items: 4

1.

Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes [CUT&RUN]

(Submitter supplied) Mutations in gene regulatory elements have been associated with a wide range of complex neuropsychiatric disorders. However, due to their cell-type specificity and difficulties in characterizing their regulatory targets, the ability to identify causal genetic variants has remained limited. To address these constraints, we perform an integrative analysis of chromatin interactions, open chromatin regions and transcriptomes using promoter capture Hi-C, assay for transposase-accessible chromatin with high-throughput sequencing (ATAC-seq) and RNA sequencing, respectively, in four functionally distinct neural cell types: induced pluripotent stem cell (iPSC)-induced excitatory neurons and lower motor neurons, iPSC-derived hippocampal dentate gyrus-like neurons and primary astrocytes. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL24676
6 Samples
Download data: BW, NARROWPEAK
Series
Accession:
GSE126211
ID:
200126211
2.

Mapping cis-regulatory chromatin contacts in neural cells links neuropsychiatric disorder risk variants to target genes

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL20301 GPL24676
39 Samples
Download data: BIGWIG, TXT
Series
Accession:
GSE113483
ID:
200113483
3.

Illumina NovaSeq 6000 (Homo sapiens)

Platform
Accession:
GPL24676
ID:
100024676
4.

CUT&RUN-CTCF_iPSC-induced lower motor neurons_rep1

Organism:
Homo sapiens
Source name:
iPSC-induced lower motor neurons
Platform:
GPL24676
Series:
GSE113483 GSE126211
Download data
Sample
Accession:
GSM3593770
ID:
303593770
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db=gds|term=GSM3593770[Accession]|query=1|qty=2|blobid=MCID_6626f931e53bb618e1c489b3|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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