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Items: 3

1.

A distal super enhancer mediates estrogen-dependent mouse uterine–specific gene transcription of Insulin-like growth factor 1 (Igf1)

(Submitter supplied) Insulin-like growth factor 1 (IGF1) is primarily synthesized in and secreted from the liver; however, estrogen (E2), through E2 receptor α (ERα), increases uterine Igf1 mRNA levels. Previous ChIP-Seq analyses of the murine uterus have revealed a potential enhancer region distal from the Igf1 transcription start site (TSS) with multiple E2-dependent ERα-binding regions. Here, we show E2-dependent super enhancer–associated characteristics and suggest contact between the distal enhancer and the Igf1 TSS. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
5 related Platforms
38 Samples
Download data: BIGWIG, HIC, TXT
Series
Accession:
GSE125972
ID:
200125972
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

V.HiC

Organism:
Mus musculus
Source name:
uterus
Platform:
GPL24247
Series:
GSE125972
Download data: HIC, TXT
Sample
Accession:
GSM3587145
ID:
303587145
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Supplemental Content

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