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Items: 4

1.

Human Bacille Calmette-Guérin vaccination elicits trained immunity via the hematopoietic progenitor compartment

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL18460
75 Samples
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Series
Accession:
GSE124220
ID:
200124220
2.

Human Bacille Calmette-Guérin vaccination elicits trained immunity via the hematopoietic progenitor compartment [bone marrow]

(Submitter supplied) Induction of trained immunity by human Bacille-Calmette-Guérin (BCG) vaccination is implicated in the beneficial heterologous effects of the vaccine, but the underlying mechanisms remain elusive. We performed global transcriptome analysis of sorted progenitors from bone marrow before (D0) and 90 days after vaccination (D90). BCG vaccination induced transcriptomic myeloid priming of the hematopoietic stem and progenitor cell (HSPC) compartment marked by the upregulation of myeloid and granulocytic pathways alongside the induction of transcription factors connected to myeloid cell function, namely Hepatocyte Nuclear Factors (HNF). more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18460
39 Samples
Download data: TXT
Series
Accession:
GSE124218
ID:
200124218
3.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
4.

BCG_D10_HSPC_BM_D90

Organism:
Homo sapiens
Source name:
bone marrow
Platform:
GPL18460
Series:
GSE124218 GSE124220
Download data
Sample
Accession:
GSM3525892
ID:
303525892
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