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Items: 3

1.

Response of p53 isogenic colorectal cancer panel to 12 Gy gamma irradiation

(Submitter supplied) Though targeted homologous recombination, we developed a panel of matched colorectal cancer cell lines that differ only with respect to their endogenous TP53 status. We then used these lines to define the genes whose expression was altered following DNA damage induced by ionizing radiation. Transcriptome analyses revealed a consistent upregulation of polo-like kinase I (PLK1) as well as other genes controlling the G2/M transition in the cells whose TP53 genes were inactivated compared to those with wild type (wt ) TP53 genes. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL4133
13 Samples
Download data: TXT
Series
Accession:
GSE13886
ID:
200013886
2.

Agilent-014850 Whole Human Genome Microarray 4x44K G4112F (Feature Number version)

(Submitter supplied) This multi-pack (4X44K) formatted microarray represents a compiled view of the human genome as it is understood today. The sequence information used to design this product was derived from a broad survey of well known sources such as RefSeq, Goldenpath, Ensembl, Unigene and others. The resulting view of the human genome covers 41K unique genes and transcripts which have been verified and optimized by alignment to the human genome assembly and by Agilent's Empirical Validation process. more...
Organism:
Homo sapiens
10 DataSets
836 Series
3 Related Platforms
15415 Samples
Download data: TXT
Platform
Accession:
GPL4133
ID:
100004133
3.

DLD-1 p53 WT Colorectal cancer cells_12 Gy gamma radiation

Organism:
Homo sapiens
Source name:
DLD-1 Colorectal cancer cell line, exposed to 12Gy gamma radiation and incubated 24 hours before sample collection (channel 1) DLD-1 Colorectal cancer cell line, nonirradiated and incubated for same time as irradiated samples (channel 2)
Platform:
GPL4133
Series:
GSE13886
Download data: TXT
Sample
Accession:
GSM349760
ID:
300349760
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