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Items: 4

1.

Amino acids availability and subsequent metabolic reprogramming sustain endocrine resistance in breast cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Non-coding RNA profiling by array
Platforms:
GPL14550 GPL15018
18 Samples
Download data: TXT
Series
Accession:
GSE120931
ID:
200120931
2.

Amino acids availability and subsequent metabolic reprogramming sustain endocrine resistance in breast cancer (mRNA)

(Submitter supplied) The majority of breast tumours express oestrogen receptor (ER) and receive endocrine therapy (ET) as standard care. Despite its efficacy, ~40% of women relapse with endocrine therapy-resistant (ETR) disease. A global transcription analysis and subsequent integrative approaches of ETR cells showed a deregulated node between miR-23b-3p and the amino acids transporter SLC6A14. Mechanistic analysis supports a model in which such deregulation impairs amino acids metabolism in the ETR cells with subsequent activation of autophagy and enhanced aspartate and glutamate import mediated by the SLC1A2 transporter. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL14550
9 Samples
Download data: TXT
Series
Accession:
GSE120929
ID:
200120929
3.

Agilent-028004 SurePrint G3 Human GE 8x60K Microarray (Probe Name Version)

(Submitter supplied) SurePrint G3 Human GE 8x60K Microarray *** The ID column includes the Agilent Probe Names. A different version of this platform with the Agilent Feature Extraction feature numbers in the ID column is assigned accession number GPL13607. Protocol: see manufacturer's web site at http://www.agilent.com/
Organism:
Homo sapiens
383 Series
1 Related Platform
8117 Samples
Download data
Platform
Accession:
GPL14550
ID:
100014550
4.

Breast adenocarcinoma cell line MCF7 – Long Term Estrogen Deprived (LTED) – rep3

Organism:
Homo sapiens
Source name:
Breast adenocarcinoma
Platform:
GPL14550
Series:
GSE120929 GSE120931
Download data: TXT
Sample
Accession:
GSM3421730
ID:
303421730
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Supplemental Content

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