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Items: 3

1.

A genome-wide framework for mapping gene regulation via cellular genetic screens

(Submitter supplied) Over one million candidate regulatory elements have been identified across the human genome, but nearly all are unvalidated and their target genes uncertain. Approaches based on human genetics are limited in scope to common variants, and in resolution by linkage disequilibrium. We present a multiplex, eQTL-inspired framework for mapping enhancer-gene pairs by introducing random combinations of CRISPR/Cas9-mediated perturbations to each of many cells, followed by single-cell RNA-seq. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL24676
53 Samples
Download data: MTX, RDS, TSV, TXT
Series
Accession:
GSE120861
ID:
200120861
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

CRISPRi singleton (eNMU) Bulk-seq

Organism:
Homo sapiens
Source name:
K562 cell line
Platform:
GPL18573
Series:
GSE120861
Download data
Sample
Accession:
GSM3417257
ID:
303417257
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