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Items: 3

1.

Runx/Cbfβ complexes protect ILC2s from exhaustion during allergic airway inflammation

(Submitter supplied) Group 2 innate lymphoid cells (ILC2s) have tissue-resident competence and contribute to the pathogenesis of allergic diseases. Therefore, there should be mechanisms to maintain the capacity of ILC2s to produce TH2 cytokines under chronic inflammatory conditions. Here, we report that Runx proteins are essential to prevent exaggerated activation of ILC2, in part by antagonizing GATA-3 function at steady state. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18480 GPL17021
30 Samples
Download data: TXT, WIG
Series
Accession:
GSE111871
ID:
200111871
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

Lung_ILC2_WT_IL2_7_33_ChIP-seq_gata3_rp1

Organism:
Mus musculus
Source name:
Lung ILC2
Platform:
GPL18480
Series:
GSE111871
Download data: WIG
Sample
Accession:
GSM3387251
ID:
303387251
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db=gds|term=GSM3387251[Accession]|query=1|qty=2|blobid=MCID_66746b308c5d4760e2a6a67c|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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