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Items: 4

1.

Differential Gene Expression in Pulmonary Artery Endothelial Cells Exposed to Sickle Cell Plasma

(Submitter supplied) Clinical variability in sickle cell disease (SCD) suggests a role for extra-erythrocytic factors in the pathogenesis of vasoocclusion. We hypothesized that one potential factor, endothelial dysfunction, results from induction of phenotypic changes by circulating factors in SCD patients. The database reports gene expression in cultured human pulmonary artery endothelial cells (HPAEC) exposed to plasma from: a) sickle acute chest syndrome (ACS) patients (samples ; b) SCD patients at steady-state and c) normal volunteers using microarrays (U133A-B GeneChip Affymetrix). more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Datasets:
GDS1257 GDS1258
Platforms:
GPL97 GPL96
65 Samples
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Series
Accession:
GSE1849
ID:
200001849
2.
Full record GDS1258

Sickle cell plasma effect on pulmonary artery endothelial cells (HG-U133B)

Expression profiling of pulmonary artery endothelial cells exposed to plasma from sickle cell disease (SCD) patients with sickle acute chest syndrome or from SCD patients at steady state. Results provide insight into the role of extra-erythrocytic factors in sickle cell vasoocclusion.
Organism:
Homo sapiens
Type:
Expression profiling by array, count, 3 disease state sets
Platform:
GPL97
Series:
GSE1849
32 Samples
Download data
DataSet
Accession:
GDS1258
ID:
1258
3.

[HG-U133B] Affymetrix Human Genome U133B Array

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html June 03, 2009: annotation table updated with netaffx build 28 June 21, 2012: annotation table updated with netaffx build 32 July 01, 2016: annotation table updated with netaffx build 35 Protocol: see manufacturer's web site The U133 set includes 2 arrays with a total of 44928 entries and was indexed 29-Jan-2002. more...
Organism:
Homo sapiens
51 DataSets
165 Series
2 Related Platforms
7917 Samples
Download data
Platform
Accession:
GPL97
ID:
100000097
4.

sc8-B

Organism:
Homo sapiens
Source name:
HPAEC
Platform:
GPL97
Series:
GSE1849
Dataset:
GDS1258
Download data
Sample
Accession:
GSM32691
ID:
300032691
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Supplemental Content

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