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Items: 4

1.

DNA accessibility is not the primary determinant of chromatin-mediated gene regulation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Saccharomyces cerevisiae
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL19057 GPL19756
98 Samples
Download data: BW
Series
Accession:
GSE115693
ID:
200115693
2.

DNA accessibility is not the primary determinant of chromatin-mediated gene regulation (mouse)

(Submitter supplied) DNA accessibility is thought to be of major importance in regulating gene expression. We test this hypothesis using a restriction enzyme as a probe of chromatin structure and as a proxy for transcription factors. We measured the digestion rate and the fraction of accessible DNA at all genomic AluI sites in budding yeast and mouse liver nuclei. Hepatocyte DNA is more accessible than yeast DNA, consistent with longer linkers between nucleosomes, and indicating that DNA accessibility is primarily determined by nucleosome spacing. more...
Organism:
Mus musculus
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL19057
24 Samples
Download data: BW
Series
Accession:
GSE115691
ID:
200115691
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

Experiment A - 160 units AluI

Organism:
Mus musculus
Source name:
Experiment A - 160 units AluI
Platform:
GPL19057
Series:
GSE115691 GSE115693
Download data: BW
Sample
Accession:
GSM3187774
ID:
303187774
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