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Items: 3

1.

Patient adipose stem cell-derived adipocytes reveal genetic variation that predicts anti-diabetic drug response

(Submitter supplied) Thiazolidinedione drugs (TZDs) target the transcriptional activity of PPARg to reverse insulin resistance in type 2 diabetes, but side effects limit their clinical use. Here, using human adipose stem cell-derived adipocytes, we demonstrate that single-nucleotide polymorphisms (SNPs) were enriched at sites of patient-specific PPARg binding, which correlated with the individual-specific effects of TZD rosiglitazone (rosi) on gene expression. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11154 GPL24676
62 Samples
Download data: BIGWIG, TXT
2.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
3.

P5_Adipocytes_DMSO_3

Organism:
Homo sapiens
Source name:
Adipocytes
Platform:
GPL11154
Series:
GSE115421
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Sample
Accession:
GSM3177946
ID:
303177946
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db=gds|term=GSM3177946[Accession]|query=1|qty=2|blobid=MCID_6620858236ac342f8a838622|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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