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Items: 3

1.

Chromatin Signatures in Multipotent Human HSCs Indicate the Fate of Bivalent Genes during Differentiation

(Submitter supplied) Histone modifications have been implicated in stem cell maintenance and differentiation. We have analyzed genome-wide changes in gene expression and histone modifications during differentiation of multipotent human primary hematopoietic stem cells/progenitor cells (HSCs/HPCs) into erythrocyte precursors. Our data indicate that H3K4me1, H3K9me1, and H3K27me1 associate with enhancers of differentiation genes prior to their activation and correlate with basal expression, suggesting that these monomethylations are involved in the maintenance of activation potential required for differentiation. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by array
Platforms:
GPL570 GPL9052
24 Samples
Download data: BED, CEL, CHP, TXT
2.

Illumina Genome Analyzer (Homo sapiens)

Platform
Accession:
GPL9052
ID:
100009052
3.

CD133-H2AZ

Organism:
Homo sapiens
Source name:
CD133+ cells
Platform:
GPL9052
Series:
GSE12646
Download data: BED, TXT
Sample
Accession:
GSM317582
ID:
300317582
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Supplemental Content

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