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Items: 3

1.

Nodal signaling maintains H3K18ac landscape to promote mesendodermal differentiation through TRIM33

(Submitter supplied) The epigenome of a cell is established and maintained by chromatin modifiers and remodelers, which are recruited to the chromatin by specific transcription factors. In this report, we show that nodal cross-talks with the epigenome through TRIM33-H3K18ac to mediate mesendodermal genes expression. The chromatin accessibility at mesendodermal genes depends on TRIM33. Moreover, histone acetylation is essential for TRIM33 recruitment to many nodal target genes involved in mesendodermal differentiation. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21273 GPL17021
23 Samples
Download data: WIG, XLSX
Series
Accession:
GSE115169
ID:
200115169
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

H3K18ac ChIP-seq ES

Organism:
Mus musculus
Source name:
mouse embryonic stem cell
Platform:
GPL21273
Series:
GSE115169
Download data: WIG
Sample
Accession:
GSM3168489
ID:
303168489
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