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Items: 3

1.

Single-Cell RNA-Seq Reveals Dynamic Early Embryonic-like Programs during Chemical Reprogramming

(Submitter supplied) We profile 36,199 single-cell transcriptomes at multiple timepoints throughout a highly efficient chemical reprogramming system using RNA-sequencing and reconstruct their progression trajectories. Through identifying sequential molecular events, we reveal that the dynamic early embryonic-like programs account for successful reprogramming from XEN-like state to pluripotency, including the transcriptomic signature of concomitant two-cell (2C) embryonic-like and early pluripotency program and the epigenetic signature of notable genome-wide DNA demethylation.
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platform:
GPL21273
30 Samples
Download data: BEDGRAPH, XLSX
Series
Accession:
GSE114952
ID:
200114952
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

scRNA-Seq_SI D12

Organism:
Mus musculus
Source name:
Intermediate cells on stage I day 12 during chemical reprogramming of MEFs
Platform:
GPL21273
Series:
GSE114952
Download data
Sample
Accession:
GSM3160736
ID:
303160736
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Supplemental Content

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