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Items: 3

1.

Regulatory Discrimination of mRNAs by FMRP Controls Adult Neural Stem Cell Differentiation

(Submitter supplied) Fragile X syndrome (FXS) is caused by the loss of fragile X mental retardation protein (FMRP), a translation-inhibitor RNA binding protein. The impact of FMRP-deficiency on neural function is widespread, including its regulation of adult neural stem cell (aNSC) differentiation. To assess FMRP activity, we performed ribosome profiling of aNSCs from normal and Fmr1 knockout mice, which revealed diverse gene expression changes at the mRNA and translation levels. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
Platform:
GPL19057
16 Samples
Download data: TXT, XLSX
Series
Accession:
GSE112502
ID:
200112502
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

ansc_wt_ribo_rep4

Organism:
Mus musculus
Source name:
Dentate gyrus
Platform:
GPL19057
Series:
GSE112502
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Sample
Accession:
GSM3071474
ID:
303071474
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