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Items: 3

1.

Identification of Novel Regulatory Genes in APAP Induced Hepatocyte Toxicity by a Genome-Wide CRISPR-Cas9 Screen

(Submitter supplied) Acetaminophen (APAP) is a commonly used analgesic responsible for more than half of acute liver failure cases. Identification of previously unknown genetic risk factors would provide mechanistic insights and novel therapeutic targets for APAP-induced liver injury. This study used a genome-wide CRISPR-Cas9 screen to evaluate genes that are protective against, or cause susceptibility to, APAP-induced liver injury. more...
Organism:
Homo sapiens; Escherichia coli
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL20045 GPL18460
12 Samples
Download data: TXT
Series
Accession:
GSE112463
ID:
200112463
2.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
3.

T0_rep1

Organism:
Homo sapiens
Source name:
HuH7 human hepatocarcinoma cell line
Platform:
GPL18460
Series:
GSE112463
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Sample
Accession:
GSM3070503
ID:
303070503
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