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Items: 3

1.

Dominant roles of B cells in the initiation of CD4 T cell response to a virus-derived nanoparticle antigen

(Submitter supplied) Nanoparticles, including virus-like particles (VLP), are attractive candidates as carriers for vaccines and drug delivery. However, little is known about how they are targeted to the immune system in vivo. Using RNA phage Qb-derived VLP (Qb-VLP) as a model antigen, we found surprisingly that antigen-specific B cells, instead of dendritic cells (DCs), were the dominant antigen presenting cells that initiate the naïve CD4 T cell activation, and were sufficient to induce T follicular helper cell development in the absence of DCs. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21273 GPL24247
12 Samples
Download data: TXT
Series
Accession:
GSE112351
ID:
200112351
2.

Illumina NovaSeq 6000 (Mus musculus)

Platform
Accession:
GPL24247
ID:
100024247
3.

day3-PC-cell-RNA.rep3

Organism:
Mus musculus
Source name:
antigen stimulated day3 PCs
Platform:
GPL24247
Series:
GSE112351
Download data: TXT
Sample
Accession:
GSM3068227
ID:
303068227
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db=gds|term=GSM3068227[Accession]|query=1|qty=2|blobid=MCID_65dd3c2a22cedd048f50bfd7|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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