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Items: 3

1.

The long noncoding RNA lnc-ob1 facilitates bone formation by upregulating Osterix in osteoblasts

(Submitter supplied) Long noncoding RNAs (lncRNAs) have emerged as integral regulators of physiology and disease, but specific roles of lncRNAs in bone disease remain largely unknown. Here, we show that lnc-ob1 regulates osteoblast activity and bone formation in mice by upregulating the osteogenic transcription factor Osterix. Expression of lnc-ob1 is enriched in osteoblasts and upregulated during osteoblastogenesis. We demonstrate that osteoblast-specific knock-in of lnc-ob1 enhances bone formation and increases bone mass. more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL21273 GPL20795
6 Samples
Download data: TXT
Series
Accession:
GSE112318
ID:
200112318
2.

HiSeq X Ten (Mus musculus)

Platform
Accession:
GPL21273
ID:
100021273
3.

mBMSC_2_week

Organism:
Mus musculus
Source name:
BMSCs
Platform:
GPL21273
Series:
GSE112318
Download data: TXT
Sample
Accession:
GSM3067607
ID:
303067607
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db=gds|term=GSM3067607[Accession]|query=1|qty=3|blobid=MCID_667489cb8c5d4760e2a90b17|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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