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Items: 3

1.

Association with Aurora-A controls N-MYC-dependent promoter escape and pause release of RNA polymerase II during the cell cycle

(Submitter supplied) MYC proteins bind globally to active promoters and promote transcriptional elongation by RNA polymerase II (RNAPII). To identify effector proteins that mediate this function, we performed mass spectrometry on N-MYC complexes in neuroblastoma cells. The analysis shows that N-MYC forms complexes with TFIIIC, TOP2A and RAD21, a subunit of cohesin. N-MYC and TFIIIC bind to overlapping sites in thousands of RNAPII promoters and intergenic regions. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL10999
50 Samples
Download data: BEDGRAPH, TXT, WIG
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

SHEP_NMYCER_8WG16_plusOHT

Organism:
Homo sapiens
Source name:
SH-EP-NMYCER
Platform:
GPL18573
Series:
GSE78957
Download data: BEDGRAPH
Sample
Accession:
GSM3036232
ID:
303036232
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Supplemental Content

db=gds|term=GSM3036232[Accession]|query=1|qty=2|blobid=MCID_66237592e53bb618e17877a4|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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