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Items: 4

1.

Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells.

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL20301 GPL21290 GPL16791
80 Samples
Download data: BW
Series
Accession:
GSE110472
ID:
200110472
2.

Helios enhances the preferential differentiation of human fetal CD4+ naïve T cells into regulatory T cells. [Epigenetics]

(Submitter supplied) Human fetal naïve T cells preferentially differentiate into CD25hiFOXP3hi regulatory T (Treg) cells upon T cell receptor (TCR) stimulation, which contribute to the generation of immunotolerance in the developing human fetus. We utilized ATACseq and H3K27ac ChIPseq to characterize the human fetal naive T cell epigenome relative to that of adult naive T cells and Treg cells. Fetal naive T cells share a partial Treg epigenome with increased chromatin accessibility and H3K27ac enrichment at a subset of Treg-specific enhancers.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL16791 GPL20301
30 Samples
Download data: BW
Series
Accession:
GSE110468
ID:
200110468
3.

Illumina HiSeq 4000 (Homo sapiens)

Platform
Accession:
GPL20301
ID:
100020301
4.

H3K27ac_ANrep2

Organism:
Homo sapiens
Source name:
Human PBMCs
Platform:
GPL20301
Series:
GSE110468 GSE110472
Download data: BW
Sample
Accession:
GSM2991634
ID:
302991634
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Supplemental Content

db=gds|term=GSM2991634[Accession]|query=1|qty=2|blobid=MCID_661b74f56bc2bd5af4bbe272|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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