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Items: 4

1.

Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18460
20 Samples
Download data: BED, BIGWIG, TXT
Series
Accession:
GSE106923
ID:
200106923
2.

Tissue-specific transcription reprogramming promotes liver metastasis of colorectal cancer (ChIP-Seq)

(Submitter supplied) Metastasis is the cause of death for 90% of cancer patients, but little is known about how cancer cells adapt to and colonize new tissue environments. Using clinical samples and primary/metastatic cell lines, we found metastatic colorectal cancer (CRC) cells lose their colon-specific gene transcription program and gain a liver-specific gene transcription program as they metastasize in the liver. We revealed this transcription reprogramming is driven by a reshaped epigenetic landscape of both typical and super-enhancers. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18460
12 Samples
Download data: BED, BIGWIG
Series
Accession:
GSE106921
ID:
200106921
3.

Illumina HiSeq 1500 (Homo sapiens)

Platform
Accession:
GPL18460
ID:
100018460
4.

SW480_H3K4me3

Organism:
Homo sapiens
Source name:
SW480 cell line
Platform:
GPL18460
Series:
GSE106921 GSE106923
Download data: BED, BIGWIG
Sample
Accession:
GSM2857643
ID:
302857643
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