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Items: 4

1.

In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors [H1 differentiation protocol]

(Submitter supplied) Regeneration of injured human heart muscle is limited and an unmet clinical need. There are no methods for the reproducible generation of clinical quality stem-cell-derived cardiovascular progenitors (CVPs). We identified laminin-221 (LN-221) as the most likely expressed cardiac laminin. We produced it as human recombinant protein, and showed that LN-221 promotes differentiation of pluripotent hESCs towards cardiomyocyte lineage and downregulates pluripotency and teratoma associated genes. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
44 Samples
Download data: TXT
Series
Accession:
GSE101132
ID:
200101132
2.

In vivo generation of post-infarct human cardiac muscle by laminin-promoted cardiovascular progenitors

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below and contains: bulk RNA-seq of two time series of a xeno-free human cardiomyocyte differentiation protocol starting from HS1001 and H1 hECSs until day 94 cardiomyocytes, single cell sequencing of cardiovascular progenitors (H1 and HS1001-derived cardiovascular progenitors at day 9 and 11) and bulk RNA-Seq of H1 hECSs that have been transferred to a LN-221 matrix. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
88 Samples
Download data
Series
Accession:
GSE100725
ID:
200100725
3.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
4.

H1_D11_7

Organism:
Homo sapiens
Source name:
H1 from WiCell International
Platform:
GPL21290
Series:
GSE100725 GSE101132
Download data
Sample
Accession:
GSM2699672
ID:
302699672
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