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Items: 4

1.

PML is a ROS sensor activating p53 upon oxidative stress

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by array
Platforms:
GPL17692 GPL11533 GPL17400
30 Samples
Download data: CEL
Series
Accession:
GSE100617
ID:
200100617
2.

Gene expression profiling of Pml wt and Pml KO mice liver with acetaminophen (apap) overdose (300mg/kg) i.p.

(Submitter supplied) The Pml gene is essential to the formation of PML nuclear bodies, domains which have been associated with various functions such as apoptosis/senescence, DNA repair and cell proliferation( Lallemand-Breitenbach 2010). PML-NBs formation is regulated by cellular stress including oxidative stress(Jeanne 2010, de The 2012). To investigate the role of PML in ROS response in vivo, we analyse the expression difference to the acetaminophen toxicity, which is initiated by ROS, in Pml wt and Pml KO mice.
Organism:
Mus musculus
Type:
Expression profiling by array
Platform:
GPL11533
12 Samples
Download data: CEL
Series
Accession:
GSE100616
ID:
200100616
3.

[MoGene-1_1-st] Affymetrix Mouse Gene 1.1 ST Array [transcript (gene) version]

(Submitter supplied) Affymetrix submissions are typically submitted to GEO using the GEOarchive method described at http://www.ncbi.nlm.nih.gov/projects/geo/info/geo_affy.html MoGene-1_1-st-v1.na31.mm9.transcript.csv #%create_date=Fri Aug 27 17:50:02 2010 PDT #%chip_type=MoGene-1_1-st-v1 #%lib_set_name=MoGene-1_1-st #%lib_set_version=v1 #%genome-species=Mus musculus #%genome-version=mm9 #%genome-version-ucsc=mm9 #%genome-version-ncbi=37 #%genome-version-create_date=2007-07-00 #%genome-lifted-method=liftOver #%genome-lifted_from-species=Mus musculus #%genome-lifted_from-version-ucsc=mm8 #%genome-lifted_from-version-ncbi=36 #%netaffx-annotation-date=2010-07-15 #%netaffx-annotation-netaffx-build=31 Protocol: see manufacturer's web site
Organism:
Mus musculus
10 DataSets
174 Series
7 Related Platforms
4230 Samples
Download data
Platform
Accession:
GPL11533
ID:
100011533
4.

Pml wt_apap6h_2

Organism:
Mus musculus
Source name:
Pml wt liver, 6h after apap ip
Platform:
GPL11533
Series:
GSE100616 GSE100617
Download data: CEL
Sample
Accession:
GSM2688976
ID:
302688976
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