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Items: 4

1.

HIV-1 infection of human monocyte-derived dendritic cells with and without the integrase inhibitor, Raltegravir

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by array; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL18573 GPL17077
56 Samples
Download data: BW, TXT
Series
Accession:
GSE100377
ID:
200100377
2.

HIV-1 infection of human monocyte-derived dendritic cells with and without the integrase inhibitor, Raltegravir (gene expression).

(Submitter supplied) Myeloid dendritic cells (DCs) have the innate capacity to sense pathogens and orchestrate immune responses. However, DCs do not mount efficient immune responses to HIV-1, due to potent restriction at the level of reverse transcription. Here, we uncover that when reverse transcription is allowed to proceed, DCs detect HIV-1 in distinct phases, before and after integration. Blocking integration suppressed, but did not abolish, activation of the transcription factor, IRF3, interferon responses, and DC maturation. more...
Organism:
Homo sapiens
Type:
Expression profiling by array
Platform:
GPL17077
32 Samples
Download data: TXT
Series
Accession:
GSE100374
ID:
200100374
3.

Agilent-039494 SurePrint G3 Human GE v2 8x60K Microarray 039381 (Probe Name version)

(Submitter supplied) SurePrint G3 Human GE v2 8x60K Microarray Design ID: 039494 Design Format: 8 x 60 K Control Grid: IS-62976-8-V2_60kby8_GX_EQC_201000210 Build Version: hg19:GRCh37:Feb2009 Arrays of this design have barcodes that begin with 16039494 or 2539494. Orientation: Features are numbered numbered Left-to-Right, Top-to-Bottom as scanned by an Agilent scanner (barcode on the left, DNA on the back surface, scanned through the glass), matching the FeatureNum output from Agilent's Feature Extraction software. more...
Organism:
Homo sapiens
574 Series
1 Related Platform
9521 Samples
Download data
Platform
Accession:
GPL17077
ID:
100017077
4.

D187_HIV_32h

Organism:
Homo sapiens
Source name:
monocyte-derived dendritic cells infected with HIV-GFP in the presence of Vpx, time (hours): 32, drug: none, donor: D187
Platform:
GPL17077
Series:
GSE100374 GSE100377
Download data: TXT
Sample
Accession:
GSM2679715
ID:
302679715
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