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Items: 4

1.

Systematic evaluation of variability in ChIP-chip experiments using predefined DNA targets

(Submitter supplied) The most widely used method for detecting genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array platforms, amplification procedures, and signal detection algorithms in a simulated ChIP-chip experiment. Mixtures of human genomic DNA and "spike-ins" comprised of nearly 100 human sequences at various concentrations were hybridized to four tiling array platforms by eight independent groups. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by genome tiling array
6 related Platforms
47 Samples
Download data: CEL, GFF, PAIR, TXT
Series
Accession:
GSE10114
ID:
200010114
2.

ENCODE spikein, amplified DNA samples, NimbleGen arrays

(Submitter supplied) The goals of the study were to assess array platform performance and analysis algorithm performance. The most widely used method for detecting genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array platforms, amplification procedures, and signal detection algorithms in a simulated ChIP-chip experiment. more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by genome tiling array
Platform:
GPL3980
3 Samples
Download data: PAIR
Series
Accession:
GSE10076
ID:
200010076
3.

UC Davis Human ENCODE array

(Submitter supplied) as described in http://www.nimblegen.com/products/chip/new_designs.html
Organism:
Homo sapiens
10 Series
72 Samples
Download data
Platform
Accession:
GPL3980
ID:
100003980
4.

ENCODE spikein competition, amplified sample, NimbleGen array 96391

Organism:
Homo sapiens
Source name:
DNA plus artificial spike-in DNA. Source of DNA: Roche commercial DNA. (channel 1) DNA without spikein (background DNA). Source of DNA: Roche commercial DNA. (channel 2)
Platform:
GPL3980
Series:
GSE10076 GSE10114
Download data: PAIR
Sample
Accession:
GSM254807
ID:
300254807
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