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Items: 3

1.

Sirtuin 1-chromatin-binding dynamics point to a common mechanism regulating microglial inflammatory targets in SIV infection and in the aging brain

(Submitter supplied) Microglia are critical regulators in neurodegenerative disorders. Since HIV infection results in neurological perturbations that are similar to those in aging, we examined microglial changes that might resemble aging, using SIV infection in rhesus macaques to model neuroAIDS. We found that Sirt-1, a molecule that impacts survival and health in many models, was decreased in infected macaques. The role of Sirt-1 in neuroAIDS is unknown. more...
Organism:
Macaca mulatta
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL21120 GPL19129
8 Samples
Download data: BW
Series
Accession:
GSE95793
ID:
200095793

SRA Run Selector

2.

Illumina NextSeq 500 (Macaca mulatta)

Organism:
Macaca mulatta
44 Series
1483 Samples
Download data
Platform
Accession:
GPL21120
ID:
100021120

3.

208_Sirt1_Rh_i87

Organism:
Macaca mulatta
Source name:
Microglia
Platform:
GPL21120
Series:
GSE95793
Download data: BW
Sample
Accession:
GSM2526074
ID:
302526074

SRA Run Selector

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db=gds|term=GSM2526074[Accession]|query=1|qty=2|blobid=MCID_6787ee039df2236507173d7b|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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