GSM2496439[Accession] - GEO DataSets

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Items: 4

Select item 2000951161.

The nuclear matrix associating protein HNRNPU functions as a key regulator of 3D genome architecture

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.

Organism:: Mus musculus

Type:: Expression profiling by high throughput sequencing; Other; Genome binding/occupancy profiling by high throughput sequencing

Platforms:: GPL16417 GPL10448 GPL21273
28 Samples

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Series

Accession:: GSE95116

ID:: 200095116

PubMed Full text in PMC Similar studies Analyze with GEO2R

Select item 2000951132.

The nuclear matrix associating protein HNRNPU functions as a key regulator of 3D genome architecture [ChIP-Seq 1]

(Submitter supplied) Higher-order chromatin conformation plays critical role in regulating gene expression and biological development, here we show that HNRNPU, a nuclear matrix attachment factor, is a regulator of 3D genome architecture at multiple levels in mouse hepatocytes. We demonstrate that depletion of HNRNPU results into a global reorganization of nuclear bodies and re-localization of chromatin towards nuclear periphery. more...