GEO DataSets

(Submitter supplied) The most widely used method for detecting genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array platforms, amplification procedures, and signal detection algorithms in a simulated ChIP-chip experiment. Mixtures of human genomic DNA and "spike-ins" comprised of nearly 100 human sequences at various concentrations were hybridized to four tiling array platforms by eight independent groups. more...

Organism:

Homo sapiens

Type:

Genome binding/occupancy profiling by genome tiling array

Platform:

GPL4559

6 Samples

Download data: PAIR

(Submitter supplied) The most widely used method for detecting genome-wide protein-DNA interactions is chromatin immunoprecipitation on tiling microarrays, commonly known as ChIP-chip. Here, we conducted the first objective analysis of tiling array platforms, amplification procedures, and signal detection algorithms in a simulated ChIP-chip experiment. Mixtures of human genomic DNA and "spike-ins" comprised of nearly 100 human sequences at various concentrations were hybridized to four tiling array platforms by eight independent groups. more...

Organism:

Homo sapiens

Type:

Genome binding/occupancy profiling by genome tiling array

6 related Platforms

47 Samples

Download data: CEL, GFF, PAIR, TXT

(Submitter supplied) 391K element tiling array based on NCBI35 build of the human genome (hg17) and contains overlapping 50-mer oligonucleotides, positioned at every 38 basepairs (bp) throughout the ENCODE regions. Protocol: Tiling array; see NimbleGen website. Contains one 50-mer every 38 nts.

Organism:

Homo sapiens

6 Series

128 Samples

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