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Items: 4

1.

Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency.

(Submitter supplied) The mechanisms underlying enhancer activation and the extent to which enhancer-promoter rewiring contributes to spatiotemporal gene expression are not well understood. Using integrative and time resolved analyses we show that the extensive transcriptome and epigenome resetting during the conversion between ‘serum-’ and ‘2i’-states of mouse embryonic stem cells (ESCs) takes place with minimal enhancer-promoter rewiring that becomes more evident in primed-state pluripotency. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing; Other
Platforms:
GPL19057 GPL13112
194 Samples
Download data: BEDGRAPH, BIGWIG, BW
Series
Accession:
GSE92412
ID:
200092412
2.

Epigenetic modulation of a hardwired 3D chromatin landscape in two naive states of pluripotency. (RNA-seq)

(Submitter supplied) The mechanisms underlying enhancer activation and the extent to which enhancer-promoter rewiring contributes to spatiotemporal gene expression are not well understood. Using integrative and time resolved analyses we show that the extensive transcriptome and epigenome resetting during the conversion between ‘serum-’ and ‘2i’-states of mouse embryonic stem cells (ESCs) takes place with minimal enhancer-promoter rewiring that becomes more evident in primed-state pluripotency. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL13112
16 Samples
Download data: BW
Series
Accession:
GSE92403
ID:
200092403
3.

Illumina HiSeq 2000 (Mus musculus)

Platform
Accession:
GPL13112
ID:
100013112
4.

RNAseq_2i_Day3_Rep1

Organism:
Mus musculus
Source name:
Mouse Embryonic Stem Cells
Platform:
GPL13112
Series:
GSE92403 GSE92412
Download data: BW
Sample
Accession:
GSM2429114
ID:
302429114
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