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Items: 4

1.

Tamoxifen Resistance in Breast Cancer is Regulated by the EZH2-ERa-GREB1 Transcriptional Axis

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
16 Samples
Download data: TXT
Series
Accession:
GSE103243
ID:
200103243
2.

The transcriptome effect of knocking down EZH2 in TamR MCF7L

(Submitter supplied) Purpose: Increasing evidence suggests that epigenetic reprogramming contributes significantly to the development of endocrine therapy resistance in breast cancer. The goal of this work is to explore how the histone methyltransferase EZH2 interacts with ER signaling and drives the insensitiveness of breast cancer cells to the antagonistic effect of tamoxifen on ER activity. Therefore, we comprehensively analyzed the transcriptional program regulated by EZH2 in tamoxifen-resistant (TamR) MCF-7 cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL21290
4 Samples
Download data: TXT
3.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
4.

shEZH2 rep1

Organism:
Homo sapiens
Source name:
tamoxifen-resistant breast cancer cells
Platform:
GPL21290
Series:
GSE92316 GSE103243
Download data: TXT
Sample
Accession:
GSM2425621
ID:
302425621
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db=gds|term=GSM2425621[Accession]|query=1|qty=2|blobid=MCID_6677bde78c5d4760e2e3cf32|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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