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Items: 4

1.

DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [XL8 DHX9 FLASH CLIP-seq]

(Submitter supplied) Transposable elements increase genetic diversity thus making them an important part of evolution and gene regulation in all organisms that carry these sequences. Bulk of our nascent transcriptome is comprised of transposable elements that have the propensity to form strong secondary structures. It is essential to resolve such strong secondary structures to maintain normal cellular function. Here, we show that the major nuclear RNA helicase DHX9/RHA interacts and remodels embedded Alu retrotransposable elements in the human transcriptome and B1 retrotransposable elements in the mouse transcriptome. more...
Organism:
Mus musculus
Type:
Other
Platform:
GPL19057
4 Samples
Download data: BED, BIGWIG, GFF
Series
Accession:
GSE89751
ID:
200089751
2.

DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome

(Submitter supplied) Transposable elements are viewed as ‘selfish genetic elements’, yet they contribute to gene regulation and genome evolution in diverse ways. More than half of the human genome consists of transposable elements. With over 1 million insertions, Alu elements belong to the short interspersed nuclear element (SINE) family of repetitive elements, and with over 1 million insertions they make up more than 10% of the human genome. more...
Organism:
Drosophila melanogaster; Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Other
6 related Platforms
90 Samples
Download data: BED, BIGWIG
Series
Accession:
GSE85164
ID:
200085164
3.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
4.

XL8 IgG-Rb ESC repA

Organism:
Mus musculus
Source name:
embryonic stem cells
Platform:
GPL19057
Series:
GSE85164 GSE89751
Download data: BED, BIGWIG
Sample
Accession:
GSM2387774
ID:
302387774
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