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Items: 4

1.

DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome

(Submitter supplied) Transposable elements are viewed as ‘selfish genetic elements’, yet they contribute to gene regulation and genome evolution in diverse ways. More than half of the human genome consists of transposable elements. With over 1 million insertions, Alu elements belong to the short interspersed nuclear element (SINE) family of repetitive elements, and with over 1 million insertions they make up more than 10% of the human genome. more...
Organism:
Homo sapiens; Drosophila melanogaster; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
6 related Platforms
90 Samples
Download data: BED, BIGWIG
Series
Accession:
GSE85164
ID:
200085164
2.

DHX9 suppresses spurious RNA processing defects originating from the Alu invasion of the human genome [uvCLAP CLIP-seq]

(Submitter supplied) Transposable elements increase genetic diversity thus making them an important part of evolution and gene regulation in all organisms that carry these sequences. Bulk of our nascent transcriptome is comprised of transposable elements that have the propensity to form strong secondary structures. It is essential to resolve such strong secondary structures to maintain normal cellular function. Here, we show that the major nuclear RNA helicase DHX9/RHA interacts and remodels embedded Alu retrotransposable elements in the human transcriptome and B1 retrotransposable elements in the mouse transcriptome. more...
Organism:
Homo sapiens; Drosophila melanogaster; Mus musculus
Type:
Expression profiling by high throughput sequencing; Other
4 related Platforms
52 Samples
Download data: BED, BIGWIG, NARROWPEAK
Series
Accession:
GSE85155
ID:
200085155
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

G2 control repA

Organism:
Homo sapiens
Source name:
HEK293
Platform:
GPL11154
Series:
GSE85155 GSE85164
Download data: BED
Sample
Accession:
GSM2375981
ID:
302375981
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