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Items: 4

1.

EZH1 as a key epigenetic barrier to definitive haematopoiesis during embryonic development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
58 Samples
Download data: BED, TXT, WIG
Series
Accession:
GSE89418
ID:
200089418
2.

ChIP-seq analysis of EZH1, H3K4me3 and H3K27me3 in 5F cells

(Submitter supplied) Blood develops in distinct stages. Haematopoietic progenitors in the embryo manifest restricted differentiation potential relative to definitive haematopoietic stem cells in adult bone marrow, which support lifelong multilineage haematopoiesis. To identify regulators of embryonic haematopoiesis, we screened chromatin modifiers and identified the Polycomb group protein EZH1 as a barrier to multilineage potential from pluripotent stem cells (PSCs). more...
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing
Platform:
GPL18573
15 Samples
Download data: BED, WIG
Series
Accession:
GSE89417
ID:
200089417
3.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
4.

ChIP-seq_5F_BirA-Only_rep1

Organism:
Homo sapiens
Source name:
Human MSCiPS1-derived 5F hematopoietic cells
Platform:
GPL18573
Series:
GSE89417 GSE89418
Download data: BED, WIG
Sample
Accession:
GSM2371319
ID:
302371319
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