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Items: 4

1.

EZH1 as a key epigenetic barrier to definitive haematopoiesis during embryonic development

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
4 related Platforms
58 Samples
Download data: BED, TXT, WIG
Series
Accession:
GSE89418
ID:
200089418
2.

RNA-seq analysis of EZH1 knockdown in 5F cells, or EZH1 heterozygous and homozygous knockout YS and AGM cells

(Submitter supplied) Blood develops in distinct stages. Haematopoietic progenitors in the embryo manifest restricted differentiation potential relative to definitive haematopoietic stem cells in adult bone marrow, which support lifelong multilineage haematopoiesis. To identify regulators of embryonic haematopoiesis, we screened chromatin modifiers and identified the Polycomb group protein EZH1 as a barrier to multilineage potential from pluripotent stem cells (PSCs). more...
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL16791 GPL17021
36 Samples
Download data: TXT
Series
Accession:
GSE89415
ID:
200089415
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

MSC-iPS 5F +shEZH1 D6 day 28 rep 1

Organism:
Homo sapiens
Source name:
Human MSC iPS-derived 5F hematopoietic cells
Platform:
GPL16791
Series:
GSE89415 GSE89418
Download data: TXT
Sample
Accession:
GSM2371294
ID:
302371294
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