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Items: 4

1.

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Genome binding/occupancy profiling by high throughput sequencing
Platforms:
GPL11154 GPL16791
166 Samples
Download data: WIG
Series
Accession:
GSE89129
ID:
200089129
2.

Suppression of adaptive responses to targeted cancer therapy by transcriptional repression [RNA-seq]

(Submitter supplied) Large-scale genomic profiling efforts have facilitated the characterization of molecular alterations in cancers and aided the development of targeted kinase inhibitors for a wide array of cancer types. However, resistance to these targeted therapies invariably develops and limits their clinical efficacy. Targeting tumours with kinase inhibitors induces complex adaptive survival programs that promote the persistence of a fraction of the original cancer cell population, facilitating the eventual outgrowth of inhibitor-resistant tumour clones following clonal evolution. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL11154
90 Samples
Download data: TXT
3.

Illumina HiSeq 2000 (Homo sapiens)

Platform
Accession:
GPL11154
ID:
100011154
4.

A375-D3 DMSO [lab: Hammerman-DFCI]

Organism:
Homo sapiens
Source name:
Melanoma
Platform:
GPL11154
Series:
GSE89127 GSE89129
Download data
Sample
Accession:
GSM2359192
ID:
302359192
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Supplemental Content

db=gds|term=GSM2359192[Accession]|query=1|qty=2|blobid=MCID_66feb27b75ef19692941c213|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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