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Items: 3

1.

Networks of cultured iPSC-derived neurons reveal the human synaptic activity-regulated adaptive gene program

(Submitter supplied) We studied the synaptic activity-regulated gene expression response in the human genetic background using cultured human iPSC-derived (hiPSCd) neuronal networks and networks of hiPSCd neurons mixed with mouse primary neurons. Our results confirm that genetic changes affect the synaptic activity-regulated gene program, proposing a functional mechanism how they have driven evolution of human cognitive abilities.
Organism:
Mus musculus; Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL19415 GPL11154 GPL16512
22 Samples
Download data: TXT
Series
Accession:
GSE88773
ID:
200088773
2.

Illumina NextSeq 500 (Homo sapiens; Mus musculus)

Organism:
Homo sapiens; Mus musculus
93 Series
1635 Samples
Download data
Platform
Accession:
GPL19415
ID:
100019415
3.

co-culture treated with Bic/4AP for 4 h Hs+Ms_Bic-4AP_4h_3

Organism:
Homo sapiens; Mus musculus
Source name:
hiPSC-derived neurons
Platform:
GPL19415
Series:
GSE88773
Download data: TXT
Sample
Accession:
GSM2345412
ID:
302345412
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