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Items: 4

1.

Human naive pluripotent stem cells exhibit X chromosome dampening and X-inactivation

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL16791 GPL20301
310 Samples
Download data: CGMAP, TXT
Series
Accession:
GSE87239
ID:
200087239
2.

Human naïve pluripotent stem cells exhibit X chromosome dampening and X-inactivation (RRBS)

(Submitter supplied) Naïve human embryonic stem cells (hESCs) can be derived from primed hESCs or directly from blastocysts, but their X-chromosome state has remained unresolved. We found that the inactive X-chromosome (Xi) of primed hESCs was reactivated in naïve culture conditions. Similar to cells of the blastocyst, resulting naive cells exhibited two active X-chromosomes with XIST expression and chromosome-wide transcriptional dampening, and initiated XIST-mediated X-inactivation upon differentiation. more...
Organism:
Homo sapiens
Type:
Methylation profiling by high throughput sequencing
Platform:
GPL16791
8 Samples
Download data: CGMAP
Series
Accession:
GSE87235
ID:
200087235
3.

Illumina HiSeq 2500 (Homo sapiens)

Platform
Accession:
GPL16791
ID:
100016791
4.

RRBS_UCLA1_Clone4_XIST_Neg_Rep2

Organism:
Homo sapiens
Source name:
Human embryonic stem cells
Platform:
GPL16791
Series:
GSE87235 GSE87239
Download data
Sample
Accession:
GSM2325782
ID:
302325782
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Supplemental Content

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