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Items: 4

1.

HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens; Mus musculus
Type:
Expression profiling by array; Expression profiling by high throughput sequencing; Other; Non-coding RNA profiling by high throughput sequencing
7 related Platforms
124 Samples
Download data: BED, BW, CEL, CSV
Series
Accession:
GSE86464
ID:
200086464
2.

HNRNPA2B1 regulates alternative RNA processing in the nervous system and accumulates in granules in ALS IPSC-derived motor neurons [hnRNPA2B1_small_rnaseq]

(Submitter supplied) HnRNPA2B1 encodes an RNA binding protein associated with neurodegenerative disorders. However, its function in the nervous system is unclear. Transcriptome-wide cross-linking and immunoprecipitation in mouse spinal cord discover UAGG motifs enriched within ~2,500 hnRNP A2/B1 binding sites and an unexpected role for hnRNP A2/B1 in alternative polyadenylation. Loss of hnRNP A2/B1 results in alternative splicing, including skipping of an exon in amyotrophic lateral sclerosis (ALS)-associated D-amino acid oxidase (DAO) that reduces D-serine metabolism. more...
Organism:
Homo sapiens; Mus musculus
Type:
Non-coding RNA profiling by high throughput sequencing
Platforms:
GPL16417 GPL15520
12 Samples
Download data: CSV
Series
Accession:
GSE86227
ID:
200086227
3.

Illumina MiSeq (Homo sapiens)

Platform
Accession:
GPL15520
ID:
100015520
4.

saline control 1 [human]

Organism:
Homo sapiens
Source name:
CVBiPS
Platform:
GPL15520
Series:
GSE86227 GSE86464
Download data
Sample
Accession:
GSM2298805
ID:
302298805
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