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Items: 3

1.

Niche WNT5A regulates expression of the actin regulatory pathway in regenerating repopulating hematopoietic stem cells

(Submitter supplied) We here show that the niche regulates the quality of the hematopoietic stem cells (HSCs) that are regenerated after transplantation. We find that a reduced level of Wnt5a in the niche regenerates dysfunctional HSCs, which do not successfully engraft secondary recipients. In particular, RNA sequencing shows a dysregulated Zeb1-associated gene expression of multiple genes involved in the small GTPase-dependent actin polymerization pathway. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18480
29 Samples
Download data: TXT
Series
Accession:
GSE84993
ID:
200084993
2.

Illumina HiSeq 1500 (Mus musculus)

Platform
Accession:
GPL18480
ID:
100018480
3.

OBC_WT_7

Organism:
Mus musculus
Source name:
OBC niche cell
Platform:
GPL18480
Series:
GSE84993
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Sample
Accession:
GSM2255646
ID:
302255646
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db=gds|term=GSM2255646[Accession]|query=1|qty=2|blobid=MCID_66708e26ce9c6e4cac2d1b38|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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