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Items: 3

1.

Genome-wide analysis of DNA hydroxymethylation and methylation during epstein-barr virus infection.

(Submitter supplied) Extensive DNA methylation in promoter regions is observed in gastric cancer with Epstein-barr virus (EBV) infection and EBV infection is the cause to induce this extensive hypermethylaiton phenotype in gastric epithelial cells. From transcriptome analysis, we found that TET2, one of the demethylase enzymes, was downregulated by EBV infection in gastric epithelial cell line MKN7. TET2 was overexpressed in a gastric epithelial cell line, GES1, to see its function and the hydroxymethylation, a byproduct of DNA demethylation, acquired genes by TET2 overexpression and methylation acquired genes by EBV infection were significantly overlapped. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing; Methylation profiling by high throughput sequencing
Platforms:
GPL18460 GPL18573
8 Samples
Download data: BIGWIG, GTF, XLSX
2.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
3.

GES1_WT_MeDIPseq

Organism:
Homo sapiens
Source name:
Fetal gastric mucosal cell line
Platform:
GPL18573
Series:
GSE84897
Download data: BIGWIG
Sample
Accession:
GSM2253671
ID:
302253671
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db=gds|term=GSM2253671[Accession]|query=1|qty=2|blobid=MCID_661d00826bc2bd5af4d498a3|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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