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Items: 3

1.

Artemisinins target GABA receptor signaling to induce alpha to beta cell transdifferentiation

(Submitter supplied) Type 1 diabetes is characterized by the destruction of pancreatic beta cells, and generating new insulin-producing cells from other cell types is a major aim of regenerative medicine. One promising approach is transdifferentiation of developmentally related pancreatic cell types including glucagon-producing alpha cells. In a genetic model, overexpression of the master regulatory transcription factor Pax4 or loss of its counterplayer Arx are sufficient to induce the conversion of alpha cells to functional beta-like cells. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platforms:
GPL11154 GPL21290
36 Samples
Download data: TSV
Series
Accession:
GSE84714
ID:
200084714
2.

Illumina HiSeq 3000 (Homo sapiens)

Platform
Accession:
GPL21290
ID:
100021290
3.

islet_single_cell_artemether_31

Organism:
Homo sapiens
Source name:
pancreatic islet
Platform:
GPL21290
Series:
GSE84714
Download data: TSV
Sample
Accession:
GSM2248271
ID:
302248271
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db=gds|term=GSM2248271[Accession]|query=1|qty=2|blobid=MCID_65e73ada03778d6c48674828|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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