U.S. flag

An official website of the United States government

Format
Sort by

Send to:

Choose Destination

Search results

Items: 4

1.

INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma

(Submitter supplied) This SuperSeries is composed of the SubSeries listed below.
Organism:
Homo sapiens
Type:
Genome binding/occupancy profiling by high throughput sequencing; Expression profiling by high throughput sequencing
Platforms:
GPL18573 GPL15520
31 Samples
Download data: BEDGRAPH, TXT
Series
Accession:
GSE82334
ID:
200082334
2.

INO80 governs super-enhancer-mediated oncogenic transcription and tumor growth in melanoma [RNA-seq]

(Submitter supplied) Super-enhancers (SEs) are large genomic regions with high density of enhancer marks. In cancer, SEs are found near oncogenes and dictate cancer gene expression. However, how oncogenic SEs are regulated remains poorly understood. Here, we show that INO80, a chromatin remodeling complex, is required for SE-mediated oncogenic transcription and tumor growth in melanoma. The expression of Ino80, the SWI/SNF ATPase, is elevated in melanoma cells and patient melanomas compared to normal melanocytes and benign nevi. more...
Organism:
Homo sapiens
Type:
Expression profiling by high throughput sequencing
Platform:
GPL18573
12 Samples
Download data: TXT
3.

Illumina NextSeq 500 (Homo sapiens)

Platform
Accession:
GPL18573
ID:
100018573
4.

A375_shIno80_day2_rep1

Organism:
Homo sapiens
Source name:
A375_shIno80_day2
Platform:
GPL18573
Series:
GSE82333 GSE82334
Download data: TXT
Sample
Accession:
GSM2190594
ID:
302190594
Format
Sort by

Send to:

Choose Destination

Supplemental Content

db=gds|term=GSM2190594[Accession]|query=1|qty=2|blobid=MCID_6620df5436ac342f8a8de927|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
   Taxonomic Groups  [List]
Tree placeholder
    Top Organisms  [Tree]

Find related data

Search details

See more...

Recent activity

Your browsing activity is empty.

Activity recording is turned off.

Turn recording back on

See more...
Support Center