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Items: 3

1.

Transgenic Expression Of Mitochondrial Chaperone Trap1 Accelerates Prostate Cancer Development

(Submitter supplied) Protein homeostasis, or proteostasis is critical for organelle function, including mitochondria, but its role in cancer is controversial. Here, we show that transgenic mice expressing the mitochondrial chaperone, TRAP1 in the prostate develop prostatic hyperplasia and cellular atypia. When examined on a Pten+/- background, a common alteration in prostate cancer patients, TRAP1 transgenic mice showed accelerated incidence of invasive prostatic adenocarcinoma, characterized by increased cell proliferation and reduced apoptosis, in situ. more...
Organism:
Mus musculus
Type:
Expression profiling by high throughput sequencing
Platform:
GPL19057
12 Samples
Download data: TXT
Series
Accession:
GSE81316
ID:
200081316
2.

Illumina NextSeq 500 (Mus musculus)

Platform
Accession:
GPL19057
ID:
100019057
3.

pten.Tg.2

Organism:
Mus musculus
Source name:
Mouse prostate
Platform:
GPL19057
Series:
GSE81316
Download data
Sample
Accession:
GSM2150219
ID:
302150219
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db=gds|term=GSM2150219[Accession]|query=1|qty=2|blobid=MCID_662642eb4c13c13a0680fefa|ismultiple=true|min_list=5|max_list=20|def_tree=20|def_list=|def_view=|url=/Taxonomy/backend/subset.cgi?|trace_url=/stat?
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